Mechanical and Temperature Stressor–Induced Seizure-and-Paralysis Behaviors inDrosophilaBang-Sensitive Mutants
نویسندگان
چکیده
منابع مشابه
Metabolic disruption in Drosophila bang-sensitive seizure mutants.
We examined a number of Drosophila mutants with increased susceptibility to seizures following mechanical or electrical stimulation to better understand the underlying factors that predispose neurons to aberrant activity. Several mutations in this class have been molecularly identified and suggest metabolic disruption as a possible source for increased seizure susceptibility. We mapped the bang...
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were isolated after mutagenesis by 5-azacytidine, 5-fluorouracil, or proflavine. The restricted replication of all mutants at 39 C was blocked subsequent to cell penetration and could not be attributed to heat inactivation of virus infectivity. Complementation analysis was made possible through the use of poly-L-ornithine. The members of one complementation group exhibited wild-type RNA synthes...
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ژورنال
عنوان ژورنال: Journal of Neurogenetics
سال: 2012
ISSN: 0167-7063,1563-5260
DOI: 10.3109/01677063.2012.690011